A Combination of Chitosan, Cellulose, and Seaweed Polysaccharide Inhibits Postoperative Intra-abdominal Adhesion in Rats
نویسندگان
چکیده
منابع مشابه
A survey on the influence of intra- peritoneal injection of hydrocortisone in the rate of intra abdominal adhesion bands in rats
Occurrence of adhesions after pelvic and abdominal surgery is a well known problem. Previous surgical procedures are by far the most common cause of intra abdominal a adhesion. In over 10℅ of infertile women, adhesion formation is the main cause of their problem. Moreover postoperative adhesions are the most common cause of intestinal obstruction in the Western world. Although the cause of ...
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BACKGROUND Postoperative intra-abdominal adhesions are a major complication after abdominal surgery. Although various methods have been used to prevent and treat adhesions, the effects have not been satisfactory. Emodin, a naturally occurring anthraquinone derivative and an active ingredient in traditional Chinese herbs, exhibits a variety of pharmacological effects. In our study, we demonstrat...
متن کاملNf‐κb Decoy Oligodeoxynucleotide Decreases Postoperative Intra‐abdominal Adhesion
Methods Forty female BALB/c mice were randomly assigned into 2 groups. The mice were anesthetized and then midline abdominal incision was made. Peritoneal injury was given using cytobrush until deperitonealization. The experimental group (n = 20) received NF-κB decoy oligodeoxynucleotide (NF-κB decoy ODN) in the peritoneal cavity before abdominal closure, while the control group (n = 20) receiv...
متن کاملOral tadalafil reduces intra-abdominal adhesion reformation in rats.
BACKGROUND Currently, there is no ideal agent to prevent adhesion formation. We have shown that sildenafil, a phosphodiesterase-5 (PDE-5) inhibitor, reduces post-operative adhesion formation by vasodilatation and increases fibrinolytic activity. Here, we evaluated whether tadalafil, a long-acting PDE-5 inhibitor, decreases post-operative adhesion reformation in rats. MATERIALS AND METHODS Sta...
متن کاملUse of Colchicine in Reduction or Prevention of Talc-induced Intra-abdominal Adhesion Bands
Background: Postoperative peritoneal adhesion bands are one of the most common complications caused by foreign material. Objective: To investigate the effect of colchicine on talc-induced peritoneal adhesion bands. Method: Adhesion bands were induced in 30 short hair England Guinea pigs by introduction of talc-saline solution (10 mL, 10%) into the peritoneal cavity. Afterwards, the pigs were ...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2017
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.117.244400